Arterial Inflammation
نویسندگان
چکیده
منابع مشابه
The Yin and Yang of arterial inflammation.
he recent wave of enthusiasm for including inflammation s one of the primary pathophysiologic processes in cardioascular disease has substantial merit (1). Arterial inflamation is central to plaque progression and plaque rupture. mong clinical markers of inflammation, C-reactive protein CRP), a complex pentameric protein largely of hepatic rigin, is the current gold standard (2,3). In a variety...
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CONTEXT Cardiovascular disease is increased in patients with human immunodeficiency virus (HIV), but the specific mechanisms are unknown. OBJECTIVE To assess arterial wall inflammation in HIV, using 18fluorine-2-deoxy-D-glucose positron emission tomography (18F-FDG-PET), in relationship to traditional and nontraditional risk markers, including soluble CD163 (sCD163), a marker of monocyte and ...
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متن کاملNeed to test the arterial inflammation hypothesis.
Despite intensive basic and clinical investigation, coronary artery disease remains the principal cause of death and disability in the United States. In recent years, the appreciation of arterial inflammation as an important risk factor has had considerable implications for changing our approach to managing these patients.1,2 Arterial inflammation has emerged as central to the progression of at...
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The receptor for advanced glycation end products (RAGE) is a pattern recognition receptor (PRR) that interacts with diverse endogenous ligands. Ligation of RAGE triggers a series of cellular signaling events, including the activation of transcription factor NF-kappaB, leading to the production of pro-inflammatory cytokines, and causing inflammation. While acute inflammation serves to resolve pa...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2019
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2019.02.002